abstract：:The diagnosis of single-lesion paucibacillary leprosy remains a challenge. Reviews by expert dermatopathologists and quantitative polymerase chain reaction (qPCR) results obtained from 66 single-plaque biopsy samples were compared. Histological findings were graded as high (HP), medium (MP) or low (LP) probability of ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbieri RR,Sales AM,Illarramendi X,Moraes MO,Nery JA,Moreira SJ,Sarno EN,Machado Ade M,Bozza FA

更新日期：2014-11-01 00:00:00

abstract：:This study aimed to correlate the presence of ica genes, biofilm formation and antimicrobial resistance in 107 strains of Staphylococcus epidermidis isolated from blood cultures. The isolates were analysed to determine their methicillin resistance, staphylococcal cassette chromosome mec (SCCmec) type, ica genes and bi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pinheiro L,Brito CI,Pereira VC,Oliveira Ad,Camargo CH,Cunha Mde L

更新日期：2014-11-01 00:00:00

abstract：:The characteristics of tuberculosis (TB) patients related to a chain of recent TB transmissions were investigated. Mycobacterium tuberculosis (MTB) isolates (120) were genotyped using the restriction fragment length polymorphism-IS6110 (R), spacer oligotyping (S) and mycobacterial interspersed repetitive units-variabl...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Peñuelas-Urquides K,Martínez-Rodríguez HG,Enciso-Moreno JA,Molina-Salinas GM,Silva-Ramírez B,Padilla-Rivas GR,Vera-Cabrera L,Torres-de-la-Cruz VM,Martínez-Martínez YB,Ortega-García JL,Garza-Treviño EN,Enciso-Moreno L,Saucedo-Cárd

更新日期：2014-09-01 00:00:00

abstract：:Epstein-Barr virus (EBV) plays a major role in liver pathology. Similar to other members of the herpesvirus family, EBV establishes a persistent infection in more than 90% of adults. The aim of this study was to evaluate the impact of EBV and chronic hepatitis C co-infection (HCV) on biochemical and immunological resp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Shoman S,Nabil M,Tabl A,Ghanem H,Kafrawy SE

更新日期：2014-09-01 00:00:00

abstract：:Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum malaria that continues to be a major global health problem. Brain vascular dysfunction is a main factor underlying the pathogenesis of CM and can be a target for the development of adjuvant therapies for the disease. Vascular occlusion b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Carvalho LJ,Moreira Ada S,Daniel-Ribeiro CT,Martins YC

更新日期：2014-08-01 00:00:00

abstract：:In a recent issue of Memórias do Instituto Oswaldo Cruz, published in Rio de Janeiro in February 2014 (109: 87-92), Adami et al. have published a survey reporting Mansonella parasite prevalence in the Amazon Region. This report makes a useful contribution to the existing knowledge of filarial parasite distribution wit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Luz SL,Crainey JL,Shelley AJ,Rubio M

更新日期：2014-07-01 00:00:00

abstract：:While the influence of water in Helicobacter pylori culturability and membrane integrity has been extensively studied, there are little data concerning the effect of this environment on virulence properties. Therefore, we studied the culturability of water-exposed H. pylori and determined whether there was any relatio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Guimarães NM,Azevedo NF,Vieira MJ,Figueiredo C

更新日期：2014-07-01 00:00:00

abstract：:Four diamines and three amino alcohols derived from 1-decanol, 1-dodecanol and 1,2-dodecanediol were evaluated in an in vitro assay against a mixture of trypomastigote and intracellular amastigote forms of Trypanosoma cruzi. Two of these compounds (6 and 7) showed better activity against both proliferative stages of T...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sales Júnior PA,Rezende Júnior CO,Le Hyaric M,Almeida MV,Romanha AJ

更新日期：2014-06-01 00:00:00

abstract：:Cutaneous leishmaniasis (CL) is a neglected clinical form of public health importance that is quite prevalent in the northern and eastern parts of Egypt. A comprehensive study over seven years (January 2005-December 2011) was conducted to track CL transmission with respect to both sandfly vectors and animal reservoirs...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Samy AM,Doha SA,Kenawy MA

更新日期：2014-06-01 00:00:00

abstract：:Several parasitological studies carried out in El Salvador between 2000-2012 showed a higher frequency of acute cases of Chagas disease than that in other Central American countries. There is an urgent need for improved Chagas disease surveillance and vector control programs in the provinces where acute Chagas disease...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sasagawa E,Aguilar AV,Ramírez MA,Chévez JE,Nakagawa J,Cedillos RA,Kita K

更新日期：2014-04-01 00:00:00

abstract：:Several genes related to the ubiquitin (Ub)-proteasome pathway, including those coding for proteasome subunits and conjugation enzymes, are differentially expressed during the Schistosoma mansoni life cycle. Although deubiquitinating enzymes have been reported to be negative regulators of protein ubiquitination and sh...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pereira RV,Vieira HG,Oliveira VF,Gomes Mde S,Passos LK,Borges Wde C,Guerra-Sá R

更新日期：2014-02-01 00:00:00

abstract：:In a recent article in the Reader's Opinion, advantages and disadvantages of the certification processes of interrupted Chagas disease transmission (American trypanosomiasis) by native vector were discussed. Such concept, accepted by those authors for the case of endemic situations with introduced vectors, has been bu...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Salvatella R,Irabedra P,Castellanos LG

更新日期：2014-02-01 00:00:00

abstract：:In 2004, the urban presence of Lutzomyia longipalpis was recorded for the first time in Formosa province. In 2006, the first autochthonous case of human urban visceral leishmaniasis (VL) was recorded in Misiones in the presence of the vector, along with some canine VL cases. After this first case, the vector began to ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bravo AG,Quintana MG,Abril M,Salomón OD

更新日期：2013-12-01 00:00:00

abstract：:Infusions of Aspidosperma nitidum (Apocynaceae) wood bark are used to treat fever and malaria in the Amazon Region. Several species of this family are known to possess indole alkaloids and other classes of secondary metabolites, whereas terpenoids, an inositol and the indole alkaloids harmane-3 acid and braznitidumine...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coutinho JP,Aguiar AC,dos Santos PA,Lima JC,Rocha MG,Zani CL,Alves TM,Santana AE,Pereira Mde M,Krettli AU

更新日期：2013-12-01 00:00:00

abstract：:This study aimed to analyse changes in the spatial distribution of Lutzomyia longipalpis in Posadas, an urban area located in northeastern Argentina. Data were obtained during the summer of 2007 and 2009 through two entomological surveys of peridomiciles distributed around the city. The abundance distribution pattern ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fernández MS,Santini MS,Cavia R,Sandoval AE,Pérez AA,Acardi S,Salomón OD

更新日期：2013-11-01 00:00:00

abstract：:The aim of the present study was to identify specific markers that mirror liver fibrosis progression as an alternative to biopsy when biopsy is contraindicated, especially in children. After liver biopsies were performed, serum samples from 30 hepatitis C virus (HCV) paediatric patients (8-14 years) were analysed and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nassef YE,Shady MM,Galal EM,Hamed MA

更新日期：2013-11-01 00:00:00

abstract：:Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva JR,Medeiros LC,Reis VP,Chavez JH,Munhoz TD,Borges GP,Soares OA,Campos CH,Machado RZ,Baldani CD,Silva ML,Faria JL,Silva EE,Figueiredo LT

更新日期：2013-11-01 00:00:00

abstract：:The aims of this study were to characterise the ground-level larval habitats of the mosquito Culex quinquefasciatus, to determine the relationships between habitat characteristics and larval abundance and to examine seasonal larval-stage variations in Córdoba city. Every two weeks for two years, 15 larval habitats (na...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Grech M,Sartor P,Estallo E,Ludueña-Almeida F,Almirón W

更新日期：2013-09-01 00:00:00

abstract：:Acute infection with Trypanosoma cruzi results in intense myocarditis, which progresses to a chronic, asymptomatic indeterminate form. The evolution toward this chronic cardiac form occurs in approximately 30% of all cases of T. cruzi infection. Suppression of delayed type hypersensitivity (DTH) has been proposed as a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Thé TS,Portella RS,Guerreiro ML,Andrade SG

更新日期：2013-09-01 00:00:00

abstract：:Heteroxenic and monoxenic trypanosomatids were screened for the presence of actin using a mouse polyclonal antibody produced against the entire sequence of the Trypanosoma cruzi actin gene, encoding a 41.9 kDa protein. Western blot analysis showed that this antibody reacted with a polypeptide of approximately 42 kDa i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza LC,Pinho RE,Lima CV,Fragoso SP,Soares MJ

更新日期：2013-08-01 00:00:00

abstract：:Studies were conducted to determine the selection of humans, chickens and rabbits by Culicidae in three different environments in the province of Chaco, Argentina. Mosquitoes were collected fortnightly using cylindrical metal traps containing animal bait (chickens and rabbits). The mosquitoes were collected between Ju...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Stein M,Zalazar L,Willener JA,Almeida FL,Almirón WR

更新日期：2013-08-01 00:00:00

abstract：:Triatoma jatai sp. nov. is the first new species of triatomine to be described in the state of Tocantins, in the northern region of Brazil. It was caught on rock outcrops in the wild environment and, more recently, invading homes. While T. jatai sp. nov. is morphologically similar to Triatoma costalimai, it is disting...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gonçalves TC,Teves-Neves SC,Santos-Mallet JR,Carbajal-de-la-Fuente AL,Lopes CM

更新日期：2013-06-01 00:00:00

abstract：:The presence of transmitted human immunodeficiency virus (HIV)-1 drug-resistance (TDR) at the time of antiretroviral therapy initiation is associated with failure to achieve viral load (VL) suppression. Here, we report TDR surveillance in a specific population of men who have sex with men (MSM) in Belo Horizonte, Braz...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tupinambás U,Duani H,Martins AV,Aleixo AW,Greco DB

更新日期：2013-06-01 00:00:00

abstract：:Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric oxide (NO) production. We previously demonstrated the correlation between serum levels of NO and the severity of renal disease in patients with severe leptospir...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos CS,Azevedo EC,Soares LM,Carvalho MO,dos Santos AC,das Chagas AD Jr,da Silva CL,Chagas UM,dos Reis MG,Athanazio DA

更新日期：2013-06-01 00:00:00

abstract：:To assess differentiation and relationships between Anopheles lesteri and Anopheles paraliae we established three and five iso-female lines of An. lesteri from Korea and An. paraliae from Thailand, respectively. These isolines were used to investigate the genetic relationships between the two taxa by crossing experime...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Taai K,Baimai V,Saeung A,Thongsahuan S,Min GS,Otsuka Y,Park MH,Fukuda M,Somboon P,Choochote W

更新日期：2013-05-01 00:00:00

abstract：:Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against several bacteria and fungi by the broth microdilution method. The thiosemicarbazone and semicarbazone derivatives of lapachol exhibited antimicrobial activity a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza MA,Johann S,Lima LA,Campos FF,Mendes IC,Beraldo H,Souza-Fagundes EM,Cisalpino PS,Rosa CA,Alves TM,de Sá NP,Zani CL

更新日期：2013-05-01 00:00:00

abstract：:Certifying the absence of Chagas disease transmission by native vectors lacks scientific grounds and weakens long-term control-surveillance systems to the detriment of people living under risk conditions. Instead, a regular "certification of good practice" (including vector control-surveillance, case detection/patient...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abad-Franch F,Diotaiuti L,Gurgel-Gonçalves R,Gürtler RE

更新日期：2013-04-01 00:00:00

abstract：:Visceral leishmaniasis, or kala-azar, is recognised as a serious emerging public health problem in India. In this study, environmental parameters, such as land surface temperature (LST) and renormalised difference vegetation indices (RDVI), were used to delineate the association between environmental variables and Phl...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kesari S,Bhunia GS,Chatterjee N,Kumar V,Mandal R,Das P

更新日期：2013-04-01 00:00:00

abstract：:This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and Plasmodium falciparum trophozoites. All of the extracts and compounds...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Claudino VD,da Silva KC,Cechinel Filho V,Yunes RA,Delle Monache F,Giménez A,Salamanca E,Gutierrez-Yapu D,Malheiros A

更新日期：2013-04-01 00:00:00

abstract：:The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume d...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dagger F,Valdivieso E,Marcano AK,Ayesta C

更新日期：2013-02-01 00:00:00

abstract：:Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequen...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Baio PV,Mota HF,Freitas AD,Gomes DL,Ramos JN,Sant'Anna LO,Souza MC,Camello TC,Hirata Junior R,Vieira VV,Mattos-Guaraldi AL

更新日期：2013-02-01 00:00:00

abstract：:Sequences of the cytochrome c oxidase subunit I (COI) mitochondrial gene from adults of 22 Culex (Culex) species from Argentina and Brazil were employed to assess species identification and to test the usefulness of COI for barcoding using the best close match (BCM) algorithm. A pairwise Kimura two-parameter distance ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Laurito M,Oliveira TM,Almirón WR,Sallum MA

更新日期：2013-01-01 00:00:00

abstract：:Acoustic signalling has been extensively studied in insect species, which has led to a better understanding of sexual communication, sexual selection and modes of speciation. The significance of acoustic signals for a blood-sucking insect was first reported in the XIX century by Christopher Johnston, studying the hear...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vigoder Fde M,Ritchie MG,Gibson G,Peixoto AA

更新日期：2013-01-01 00:00:00

abstract：:Iron is essential for all organisms and its availability can control the growth of microorganisms; therefore, we examined the role of iron metabolism in multibacillary (MB) leprosy, focusing on the involvement of hepcidin. Erythrograms, iron metabolism parameters, pro-inflammatory cytokines and urinary hepcidin levels...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza VN,Malaspina TS,Campanelli AP,Ghidella C,Ura S,Dalpino D,do Nascimento DC,Latini AC

更新日期：2012-12-01 00:00:00

abstract：:Non-bilayer phospholipid arrangements are three-dimensional structures that form when anionic phospholipids with an intermediate structure of the tubular hexagonal phase II are present in a bilayer of lipids. Antibodies that recognise these arrangements have been described in patients with antiphospholipid syndrome an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Baeza I,Wong-Baeza C,Valerdi E,Serafin-Lopez J,Ibáñez M,Estrada-Parra S,Wong C,Estrada-Garcia I

更新日期：2012-12-01 00:00:00

abstract：:Leprosy is an ancient disease that remains endemic and continues to be a major public health problem in some tropical countries, where it has been internationally recognized as being linked to the underdevelopment conditions. The natural course of the disease covers a wide variety of clinical conditions with systemic ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Foss NT,Motta AC

更新日期：2012-12-01 00:00:00

abstract：:This retrospective study (April-September 2003) was designed to investigate the roles of the main viruses responsible for cases of acute infantile gastroenteritis in hospitalised children up to two years of age. The viruses were identified in 64.7% (88/136) of the cases and the detection rates of rotavirus A (RVA), no...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira MS,Cubel Garcia Rde C,Xavier Mda P,Ribeiro RL,Assis RM,Mota Mdo C,Leite JP,Miagostovich MP,de Oliveira SA

更新日期：2012-12-01 00:00:00

abstract：:A new species of Brazilian phlebotomine sandfly found in Brazil, municipality of Diamantina, state of Minas Gerais, is described based on males and females collected in a quartzite cave. The body of spermathecae is continuous to the individual duct, lanky and tapering at the end, with conical shaped, not striated and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barata RA,Serra e Meira PC,Carvalho GM

更新日期：2012-12-01 00:00:00

abstract：:A vaccination campaign against pandemic influenza A (H1N1)pdm09 was held in Brazil in March 2010, using two types of monovalent split virus vaccines: an AS03-adjuvanted vaccine and a non-adjuvanted vaccine. We compared the reactogenicity of the vaccines in health professionals from a Clinical Research Institute in Rio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cerbino-Neto J,Santos AT,Gouvea MI,Pedro RS,Ramos GV,Guaraldo L,Werneck GL

更新日期：2012-11-01 00:00:00

abstract：:Artemisinin is the active antimalarial compound obtained from the leaves of Artemisia annua L. Artemisinin, and its semi-synthetic derivatives, are the main drugs used to treat multi-drug-resistant Plasmodium falciparum (one of the human malaria parasite species). The in vitro susceptibility of P. falciparum K1 and 3d...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva LF,Magalhães PM,Costa MR,Alecrim Md,Chaves FC,Hidalgo Ade F,Pohlit AM,Vieira PP

更新日期：2012-11-01 00:00:00